Gastric xanthoma in the pediatric population: A possible herald for malignancy?

Joseph D. Russell, Jacquelin Peck, Claudia Phen, Janna L. Linehan, Sara Karjoo, Johnny Nguyen, Michael J. Wilsey

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Gastric xanthoma is frequently an incidental finding on upper endoscopy in adults. Gastric xanthomas (GX) can be mistaken for malignancies and warrant prompt histologic diagnosis. The underlying etiology is not fully understood; however, it has been linked to Helicobacter pylori gastritis and gastric cancer. GX in the pediatric population is largely unreported in the literature. Because of the relative rarity, documentation with case reports are essential to provide as much data as possible to see if there is a correlation between GX and malignant potential in the pediatric population. Our group is reporting two cases, a 10-year-old male and a 7-year-old male, both who presented with chronic dysphagia, upper abdominal pain, nausea, vomiting, and loss of appetite. Upper endoscopies for both patients revealed small polypoid lesions located in the antrum with foamy histiocytes on histology, leading to the diagnosis of gastric xanthoma.

Original languageEnglish (US)
Pages (from-to)110-114
Number of pages5
JournalPediatric Gastroenterology, Hepatology and Nutrition
Issue number1
StatePublished - Jan 1 2020


  • Endoscopy
  • Helicobacter pylori
  • Lipids
  • Pediatrics
  • Stomach neoplasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hepatology
  • Gastroenterology


Dive into the research topics of 'Gastric xanthoma in the pediatric population: A possible herald for malignancy?'. Together they form a unique fingerprint.

Cite this