Fungal brain abscess in a severely burned patient

Audrey Stevens; Caitlyn Waldrop; Samuel Mandell; Kareem Abdelfattah; Brett Arnoldo; Chiaka O. Akarichi; Audra T. Clark

doi:10.1093/jbcr/irad111

Fungal brain abscess in a severely burned patient

Audrey Stevens, Caitlyn Waldrop, Samuel Mandell, Kareem Abdelfattah, Brett Arnoldo, Chiaka O. Akarichi, Audra T. Clark

Research output: Contribution to journal › Article › peer-review

Abstract

Burn patients are particularly susceptible to atypical and opportunistic infections. Here we report an unusual case of a 40-year-old previously healthy man with a 74% TBSA burn injury who developed a presumed Fusarium brain abscess. This patient had a complicated infectious course including ESBL E. coli and Elizabethkingia bacteremia and pneumonia, MRSA ventilator-associated pneumonia, Mycobacterium abscessus bacteremia, and Fusarium fungemia. After diagnosis with a fungal abscess on magnetic resonance imaging of the brain, the patient was treated with aspiration and appropriate antifungal therapies. The patient was eventually transitioned to comfort care and died on hospital day 167. This is the first published report of a Fusarium-related brain abscess since it was first reported in a case report of a burned child in 1974.

Original language	English (US)
Pages (from-to)	1253-1257
Number of pages	5
Journal	Journal of burn care & research : official publication of the American Burn Association
Volume	44
Issue number	5
DOIs	https://doi.org/10.1093/jbcr/irad111
State	Published - Sep 7 2023

Keywords

brain sbscess
burn
fungemia
fusarium

ASJC Scopus subject areas

General Medicine

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10.1093/jbcr/irad111

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title = "Fungal brain abscess in a severely burned patient",

abstract = "Burn patients are particularly susceptible to atypical and opportunistic infections. Here we report an unusual case of a 40-year-old previously healthy man with a 74% TBSA burn injury who developed a presumed Fusarium brain abscess. This patient had a complicated infectious course including ESBL E. coli and Elizabethkingia bacteremia and pneumonia, MRSA ventilator-associated pneumonia, Mycobacterium abscessus bacteremia, and Fusarium fungemia. After diagnosis with a fungal abscess on magnetic resonance imaging of the brain, the patient was treated with aspiration and appropriate antifungal therapies. The patient was eventually transitioned to comfort care and died on hospital day 167. This is the first published report of a Fusarium-related brain abscess since it was first reported in a case report of a burned child in 1974.",

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AU - Arnoldo, Brett

AU - Akarichi, Chiaka O.

AU - Clark, Audra T.

N1 - Publisher Copyright: © The Author(s) 2023. Published by Oxford University Press on behalf of the American Burn Association. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PY - 2023/9/7

Y1 - 2023/9/7

N2 - Burn patients are particularly susceptible to atypical and opportunistic infections. Here we report an unusual case of a 40-year-old previously healthy man with a 74% TBSA burn injury who developed a presumed Fusarium brain abscess. This patient had a complicated infectious course including ESBL E. coli and Elizabethkingia bacteremia and pneumonia, MRSA ventilator-associated pneumonia, Mycobacterium abscessus bacteremia, and Fusarium fungemia. After diagnosis with a fungal abscess on magnetic resonance imaging of the brain, the patient was treated with aspiration and appropriate antifungal therapies. The patient was eventually transitioned to comfort care and died on hospital day 167. This is the first published report of a Fusarium-related brain abscess since it was first reported in a case report of a burned child in 1974.

AB - Burn patients are particularly susceptible to atypical and opportunistic infections. Here we report an unusual case of a 40-year-old previously healthy man with a 74% TBSA burn injury who developed a presumed Fusarium brain abscess. This patient had a complicated infectious course including ESBL E. coli and Elizabethkingia bacteremia and pneumonia, MRSA ventilator-associated pneumonia, Mycobacterium abscessus bacteremia, and Fusarium fungemia. After diagnosis with a fungal abscess on magnetic resonance imaging of the brain, the patient was treated with aspiration and appropriate antifungal therapies. The patient was eventually transitioned to comfort care and died on hospital day 167. This is the first published report of a Fusarium-related brain abscess since it was first reported in a case report of a burned child in 1974.

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Fungal brain abscess in a severely burned patient

Abstract

Keywords

ASJC Scopus subject areas

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