From neuroanatomy to behavior: Central integration of peripheral signals regulating feeding behavior

Kevin W. Williams; Joel K. Elmquist

doi:10.1038/nn.3217

From neuroanatomy to behavior: Central integration of peripheral signals regulating feeding behavior

Kevin W. Williams, Joel K. Elmquist

Research output: Contribution to journal › Review article › peer-review

306 Scopus citations

Abstract

Over the past two centuries, prevalent models of energy and glucose homeostasis have emerged from careful anatomical descriptions in tandem with an understanding of cellular physiology. More recent technological advances have culminated in the identification of peripheral and central factors that influence neural circuits regulating metabolism. This Review highlights contributions to our understanding of peripheral and central factors regulating food intake and energy expenditure.

Original language	English (US)
Pages (from-to)	1350-1355
Number of pages	6
Journal	Nature neuroscience
Volume	15
Issue number	10
DOIs	https://doi.org/10.1038/nn.3217
State	Published - Oct 2012

ASJC Scopus subject areas

Neuroscience(all)

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10.1038/nn.3217

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title = "From neuroanatomy to behavior: Central integration of peripheral signals regulating feeding behavior",

abstract = "Over the past two centuries, prevalent models of energy and glucose homeostasis have emerged from careful anatomical descriptions in tandem with an understanding of cellular physiology. More recent technological advances have culminated in the identification of peripheral and central factors that influence neural circuits regulating metabolism. This Review highlights contributions to our understanding of peripheral and central factors regulating food intake and energy expenditure.",

author = "Williams, {Kevin W.} and Elmquist, {Joel K.}",

note = "Funding Information: The authors gratefully acknowledge M.M. Scott and L. Gautron for comments on the manuscript. This work was supported by the US National Institutes of Health (K01 DK087780 to K.W.W. and DK53301, MH61583, DK08876, DK081185 and DK71320 to J.K.E.) and by an award from the American Diabetes Association to J.K.E.",

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N2 - Over the past two centuries, prevalent models of energy and glucose homeostasis have emerged from careful anatomical descriptions in tandem with an understanding of cellular physiology. More recent technological advances have culminated in the identification of peripheral and central factors that influence neural circuits regulating metabolism. This Review highlights contributions to our understanding of peripheral and central factors regulating food intake and energy expenditure.

AB - Over the past two centuries, prevalent models of energy and glucose homeostasis have emerged from careful anatomical descriptions in tandem with an understanding of cellular physiology. More recent technological advances have culminated in the identification of peripheral and central factors that influence neural circuits regulating metabolism. This Review highlights contributions to our understanding of peripheral and central factors regulating food intake and energy expenditure.

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From neuroanatomy to behavior: Central integration of peripheral signals regulating feeding behavior

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