Abstract
Apoptosis repressor with caspase recruitment domain (ARC) is an established cytoplasmic anti-apoptotic factor relevant for cancer and metabolic disease. In this issue of Developmental Cell, McKimpson et al. show that ARC can assume potent pro-apoptotic effects in β cells of the endocrine pancreas via translocation to the nucleus.
Original language | English (US) |
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Pages (from-to) | 717-718 |
Number of pages | 2 |
Journal | Developmental cell |
Volume | 56 |
Issue number | 6 |
DOIs | |
State | Published - Mar 22 2021 |
ASJC Scopus subject areas
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- Developmental Biology
- Cell Biology