Abstract
Establishment of the maternal-fetal circulation during embryonic development is a fundamental process required for effective exchange of nutrients, waste products and signaling factors critical to all subsequent stages of fetal growth and development. Recent work has uncovered a previously unrecognized role of the transcription factor FoxO1 in the orchestration of molecular events underlying establishment of maternal-fetal circulatory interaction. These new data contribute to a larger body of literature implicating this protein in the governance of a wide array of processes during development and beyond.
Original language | English (US) |
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Journal | Transcription |
Volume | 3 |
Issue number | 5 |
DOIs | |
State | Published - 2012 |
Keywords
- Allantois
- Cardiovascular
- Circulation
- Development
- Embryogenesis
- FoxO
- Maternal-fetal circulation
- Placenta
ASJC Scopus subject areas
- Biotechnology
- Biochemistry
- Genetics