Food Allergy in Adults and Children

Elizabeth J. Mahoney, Maria C. Veling, James W. Mims

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Food allergy is defined as an adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food and is distinct from food intolerance. Clinical manifestations of food allergy are varied and involve many systems including respiratory, cutaneous, and gastrointestinal. The double-blinded placebo-controlled oral food challenge remains the gold standard for the diagnosis of IgE-mediated food allergy. Areas of ongoing research include improved understanding of determinants for the development of tolerance versus sensitization for foods, the role of diagnostic testing for specific epitopes for food allergens, and the use of oral immunotherapy for IgE-mediated food allergy.

Original languageEnglish (US)
Pages (from-to)815-833
Number of pages19
JournalOtolaryngologic Clinics of North America
Issue number3
StatePublished - Jun 1 2011


  • Food allergy
  • IgE
  • Oral food challenge
  • Peanut allergy

ASJC Scopus subject areas

  • Otorhinolaryngology


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