Fine-Needle Aspiration of Riediel's Disease: Report of a Case and Review of the Literature

Malini Harigopal, Sunati Sahoo, Wendy M. Recant, Richard M. DeMay

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations


The cytomorphological features of a case of Riedel's thyroiditis (Riedel's disease) in a 37-yr-old woman are reviewed. The patient presented with a diffusely enlarged thyroid gland with extension to carotid and jugular vessels bilaterally. A fine-needle aspiration of the right lobe of the thyroid demonstrated moderate cellularity with fragments of fibrous tissue with bland spindle-shaped cells and myofibroblasts. The patient subsequently underwent a bilateral subtotal thyroidectomy with removal of two-thirds of both lobes of the thyroid. A frozen section diagnosis of Riedel's disease was later confirmed on paraffin sections. Here we describe the cytological findings of a case of Riedel's disease and provide some helpful clues in distinguishing it from other forms of thyroiditis such as fibrosing variant of Hashimoto's thyroiditis, subacute thyroiditis, or granulomatous thyroiditis and from malignancy with which it can be confused both clinically and cytologically.

Original languageEnglish (US)
Pages (from-to)193-197
Number of pages5
JournalDiagnostic cytopathology
Issue number3
StatePublished - Mar 2004


  • Differential diagnoses
  • Fine-needle aspiration cytology
  • Riedel's disease
  • Thyroid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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