Finding Sugar in the Pantry: How Galectins Detect and Signal Lysosomal Damage

Hijai R. Shin; Roberto Zoncu

doi:10.1016/j.molcel.2018.03.017

Finding Sugar in the Pantry: How Galectins Detect and Signal Lysosomal Damage

Hijai R. Shin, Roberto Zoncu

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

In this issue of Molecular Cell, Jia et al. (2018) identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis. In this issue of Molecular Cell, Jia et al. identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis.

Original language	English (US)
Pages (from-to)	5-7
Number of pages	3
Journal	Molecular cell
Volume	70
Issue number	1
DOIs	https://doi.org/10.1016/j.molcel.2018.03.017
State	Published - Apr 5 2018
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2018.03.017

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title = "Finding Sugar in the Pantry: How Galectins Detect and Signal Lysosomal Damage",

abstract = "In this issue of Molecular Cell, Jia et al. (2018) identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis. In this issue of Molecular Cell, Jia et al. identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis.",

author = "Shin, {Hijai R.} and Roberto Zoncu",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

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AU - Zoncu, Roberto

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N2 - In this issue of Molecular Cell, Jia et al. (2018) identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis. In this issue of Molecular Cell, Jia et al. identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis.

AB - In this issue of Molecular Cell, Jia et al. (2018) identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis. In this issue of Molecular Cell, Jia et al. identify a lysosomal damage-response pathway centered on galectin 8 and 9 that feeds back on mTORC1 signaling. In response to lysosome-damaging agents, galectins inhibits mTORC1, triggering a stress response that may help restore cellular homeostasis.

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JO - Molecular cell

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Finding Sugar in the Pantry: How Galectins Detect and Signal Lysosomal Damage

Abstract

ASJC Scopus subject areas

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