Feline uveal melanoma model induced with feline sarcoma virus

D. M. Albert; J. A. Shadduck; J. L. Craft; J. Y. Niederkorn

Feline uveal melanoma model induced with feline sarcoma virus

D. M. Albert, J. A. Shadduck, J. L. Craft, J. Y. Niederkorn

Research output: Contribution to journal › Article › peer-review

Abstract

This paper describes the first animal model of a virally induced uveal melanoma. Tumors developed following the injection of an RNA tumor virus, i.e., Gardner strain feline sarcoma virus, into the anterior chamber of newborn kitterns. Histogically, the tumors were found to be iris and ciliary body melanomas, many of which showed invasion. The histology and ultrastructure of those tumors are described.

Original language	English (US)
Pages (from-to)	606-624
Number of pages	19
Journal	Investigative Ophthalmology and Visual Science
Volume	20
Issue number	5
State	Published - Jan 1 1981

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

Cite this

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title = "Feline uveal melanoma model induced with feline sarcoma virus",

abstract = "This paper describes the first animal model of a virally induced uveal melanoma. Tumors developed following the injection of an RNA tumor virus, i.e., Gardner strain feline sarcoma virus, into the anterior chamber of newborn kitterns. Histogically, the tumors were found to be iris and ciliary body melanomas, many of which showed invasion. The histology and ultrastructure of those tumors are described.",

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AB - This paper describes the first animal model of a virally induced uveal melanoma. Tumors developed following the injection of an RNA tumor virus, i.e., Gardner strain feline sarcoma virus, into the anterior chamber of newborn kitterns. Histogically, the tumors were found to be iris and ciliary body melanomas, many of which showed invasion. The histology and ultrastructure of those tumors are described.

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Feline uveal melanoma model induced with feline sarcoma virus

Abstract

ASJC Scopus subject areas

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