TY - JOUR
T1 - Fast-track cardiac anesthesia
T2 - Use of remifentanil combined with intrathecal morphine as an alternative to sufentanil during desflurane anesthesia
AU - Zarate, Eduardo
AU - Latham, Paige
AU - White, Paul F.
AU - Bossard, Robert
AU - Morse, Lisa
AU - Douning, Linda K.
AU - Shi, Chen
AU - Chi, Lei
PY - 2000
Y1 - 2000
N2 - The purpose of this cardiac fast-track study was to evaluate the use of remifentanil (R) combined with intrathecal (IT) morphine as an alternative to sufentanil (S) during desflurane anesthesia with respect to postoperative pain control. Prior to entering the operating room, patients in the R group (n = 20) received morphine, 8 μg/kg IT. Anesthesia was induced using a standardized anesthetic technique in all patients. In the R group, anesthesia was maintained with R, 0.1 μg·kg-1·min-1 in combination with desflurane 3-10%. In the S group (n = 20), patients received S 0.3 μg·kg-1·h-1 and desflurane 3-10%. There were no differences between the two groups with respect to time from arrival in the intensive care unit to tracheal extubation (5.1 ± 4.3 h vs 5.8 ± 6.7 h for R and S groups, respectively). After extubation, patients in the R group had significantly lower visual analog pain scores, reduced patient-controlled analgesic requirements, and greater satisfaction with their perioperative pain management, compared with patients in the S group. We conclude that R combined with IT morphine provided superior pain control after cardiac surgery compared with a S-based general anesthetic technique.
AB - The purpose of this cardiac fast-track study was to evaluate the use of remifentanil (R) combined with intrathecal (IT) morphine as an alternative to sufentanil (S) during desflurane anesthesia with respect to postoperative pain control. Prior to entering the operating room, patients in the R group (n = 20) received morphine, 8 μg/kg IT. Anesthesia was induced using a standardized anesthetic technique in all patients. In the R group, anesthesia was maintained with R, 0.1 μg·kg-1·min-1 in combination with desflurane 3-10%. In the S group (n = 20), patients received S 0.3 μg·kg-1·h-1 and desflurane 3-10%. There were no differences between the two groups with respect to time from arrival in the intensive care unit to tracheal extubation (5.1 ± 4.3 h vs 5.8 ± 6.7 h for R and S groups, respectively). After extubation, patients in the R group had significantly lower visual analog pain scores, reduced patient-controlled analgesic requirements, and greater satisfaction with their perioperative pain management, compared with patients in the S group. We conclude that R combined with IT morphine provided superior pain control after cardiac surgery compared with a S-based general anesthetic technique.
UR - http://www.scopus.com/inward/record.url?scp=0033868773&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033868773&partnerID=8YFLogxK
U2 - 10.1213/00000539-200008000-00006
DO - 10.1213/00000539-200008000-00006
M3 - Article
C2 - 10910832
AN - SCOPUS:0033868773
SN - 0003-2999
VL - 91
SP - 283
EP - 287
JO - Anesthesia and analgesia
JF - Anesthesia and analgesia
IS - 2
ER -