Familial pseudomembranous colitis and its relation to lincomycin therapy

Mary Jo E Harrod; Michael S. Brown; Arthur G. Weinberg; William N. Harkness; Joseph L. Goldstein

doi:10.1007/BF01070948

Familial pseudomembranous colitis and its relation to lincomycin therapy

Mary Jo E Harrod, Michael S. Brown, Arthur G. Weinberg, William N. Harkness, Joseph L. Goldstein

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Abstract

Severe pseudomembranous colitis was observed in 3 members of a single family: the father and 2 of his children. 2 of the affected family members received the antibiotic lincomycin prior to the onset of their symptoms. The findings in this family raise the possibility that antibiotic-induced pseudomembranous colitis in some patients may be the result of a pharmacogenetic interaction.

Original language	English (US)
Pages (from-to)	808-812
Number of pages	5
Journal	The American Journal of Digestive Diseases
Volume	20
Issue number	9
DOIs	https://doi.org/10.1007/BF01070948
State	Published - Sep 1 1975

ASJC Scopus subject areas

Gastroenterology

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title = "Familial pseudomembranous colitis and its relation to lincomycin therapy",

abstract = "Severe pseudomembranous colitis was observed in 3 members of a single family: the father and 2 of his children. 2 of the affected family members received the antibiotic lincomycin prior to the onset of their symptoms. The findings in this family raise the possibility that antibiotic-induced pseudomembranous colitis in some patients may be the result of a pharmacogenetic interaction.",

author = "Harrod, {Mary Jo E} and Brown, {Michael S.} and Weinberg, {Arthur G.} and Harkness, {William N.} and Goldstein, {Joseph L.}",

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AU - Goldstein, Joseph L.

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AB - Severe pseudomembranous colitis was observed in 3 members of a single family: the father and 2 of his children. 2 of the affected family members received the antibiotic lincomycin prior to the onset of their symptoms. The findings in this family raise the possibility that antibiotic-induced pseudomembranous colitis in some patients may be the result of a pharmacogenetic interaction.

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Familial pseudomembranous colitis and its relation to lincomycin therapy

Abstract

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