Expression of the gene encoding the LIM protein CRP2: A developmental profile

James R. Henderson; Doris Brown; James A. Richardson; Eric N. Olson; Mary C. Beckerle

doi:10.1177/002215540205000112

Expression of the gene encoding the LIM protein CRP2: A developmental profile

James R. Henderson, Doris Brown, James A. Richardson, Eric N. Olson, Mary C. Beckerle

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Members of the cysteine-rich protein (CRP) family are evolutionarily conserved Lin-11, Isl-1, Mac-3 (LIM) domain proteins that have been implicated in cell differentiation. Here we describe the expression pattern of the CRP family member CRP2 in mouse. Unlike other CRP family members, which are expressed primarily in muscle, CRP2 is more broadly expressed. In addition to expression in vascular smooth muscle cells, we also detect CRP2-specific transcripts in mesenchymal derivatives and several epithelia.

Original language	English (US)
Pages (from-to)	107-111
Number of pages	5
Journal	Journal of Histochemistry and Cytochemistry
Volume	50
Issue number	1
DOIs	https://doi.org/10.1177/002215540205000112
State	Published - 2002

Keywords

Development
Epithelia
Heart
Heart valves
Kidney
LIM domains
Lamina propria
Mesenchyme
Vascular smooth muscle

ASJC Scopus subject areas

Anatomy
Histology

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10.1177/002215540205000112

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title = "Expression of the gene encoding the LIM protein CRP2: A developmental profile",

abstract = "Members of the cysteine-rich protein (CRP) family are evolutionarily conserved Lin-11, Isl-1, Mac-3 (LIM) domain proteins that have been implicated in cell differentiation. Here we describe the expression pattern of the CRP family member CRP2 in mouse. Unlike other CRP family members, which are expressed primarily in muscle, CRP2 is more broadly expressed. In addition to expression in vascular smooth muscle cells, we also detect CRP2-specific transcripts in mesenchymal derivatives and several epithelia.",

keywords = "Development, Epithelia, Heart, Heart valves, Kidney, LIM domains, Lamina propria, Mesenchyme, Vascular smooth muscle",

author = "Henderson, {James R.} and Doris Brown and Richardson, {James A.} and Olson, {Eric N.} and Beckerle, {Mary C.}",

year = "2002",

doi = "10.1177/002215540205000112",

language = "English (US)",

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T1 - Expression of the gene encoding the LIM protein CRP2

T2 - A developmental profile

AU - Henderson, James R.

AU - Brown, Doris

AU - Richardson, James A.

AU - Olson, Eric N.

AU - Beckerle, Mary C.

PY - 2002

Y1 - 2002

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AB - Members of the cysteine-rich protein (CRP) family are evolutionarily conserved Lin-11, Isl-1, Mac-3 (LIM) domain proteins that have been implicated in cell differentiation. Here we describe the expression pattern of the CRP family member CRP2 in mouse. Unlike other CRP family members, which are expressed primarily in muscle, CRP2 is more broadly expressed. In addition to expression in vascular smooth muscle cells, we also detect CRP2-specific transcripts in mesenchymal derivatives and several epithelia.

KW - Development

KW - Epithelia

KW - Heart

KW - Heart valves

KW - Kidney

KW - LIM domains

KW - Lamina propria

KW - Mesenchyme

KW - Vascular smooth muscle

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DO - 10.1177/002215540205000112

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AN - SCOPUS:0036141929

SN - 0022-1554

VL - 50

SP - 107

EP - 111

JO - Journal of Histochemistry and Cytochemistry

JF - Journal of Histochemistry and Cytochemistry

IS - 1

ER -

Expression of the gene encoding the LIM protein CRP2: A developmental profile

Abstract

Keywords

ASJC Scopus subject areas

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