Abstract
We report the use of novel multicolored CdTe quantum dots (QDs) as fluorophores for biological fluorescence imaging. The CdTe QDs were prepared to exhibit emission wavelengths in the green, yellow, and red range by using trifluoroacetic acid (TFA), L-cysteine and thioglycolic acid (TGA) as surface stabilizers, respectively. The particles have good water solubility and photostability. Fluorescence imaging potential was evaluated in vitro and in vivo using a multispectral Maestro CRI Fluorescence Imaging system. The results show that different colored CdTe QDs allow sensitive detection simultaneously or separately both in vitro and in vivo against background fluorescence. The studies indicate that CdTe QDs can provide alternative fluorescent probes for biological imaging.
Original language | English (US) |
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Pages (from-to) | 1174-1177 |
Number of pages | 4 |
Journal | Journal of Nanoscience and Nanotechnology |
Volume | 8 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2008 |
Keywords
- Biological application
- CdTe
- Fluorescent imaging
- Quantum dots
ASJC Scopus subject areas
- Bioengineering
- General Chemistry
- Biomedical Engineering
- General Materials Science
- Condensed Matter Physics