Expectant use of CIC in newborns with spinal dysraphism: Report of clinical outcomes

Matthew D. Timberlake, Adam J. Kern, Richard Adams, Candice Walker, Bruce J. Schlomer, Micah A. Jacobs

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


PURPOSE: Report urologic outcomes among newborns with spinal dysraphism managed within an expectant clean intermittent catheterization (CIC) program. METHODS: Newborns were followed clinically and with serial ultrasound (US). Urodynamics (UD) and dimercaptosuccinic acid (DMSA) renal scan were obtained at 3-6 months, 1 year, 3 years, then as needed. Patients with initial evaluation after 6 months were excluded. RESULTS: Median follow-up was 3.2 years. 11/102 began catheterization for continence (median 4.0 years) and 47/102 did not start CIC. Of these, 2/58 developed a DMSA abnormality. 44/102 began CIC early, often for elevated storage pressures and febrile urinary tract infection (UTI). Of these, 20/44 developed a DMSA abnormality including 9 who had abnormality detected prior to starting CIC. Being on CIC or starting immediately upon recognition of new hydronephrosis, reflux, elevated filling pressures, or febrile UTI was associated with lower chance of DMSA abnormalities (4/17, 24%) compared to delaying CIC (16/27, 60%) (p= 0.03). CONCLUSIONS: CIC can be deferred until continence in select infants with a low risk of significant DMSA abnormality. However, immediate initiation of CIC upon recognition of risk factors is recommended as this was associated with fewer DMSA abnormalities than delaying CIC. Recommendations for expectantly-managed patients include close follow-up, serial US and UD, and prompt initiation of CIC upon recognition of new hydronephrosis, reflux, elevated storage pressures, or febrile UTIs.

Original languageEnglish (US)
Pages (from-to)319-325
Number of pages7
JournalJournal of Pediatric Rehabilitation Medicine
Issue number3-4
StatePublished - Jan 1 2017


  • Clean intermittent catheterization
  • DMSA abnormalities
  • Expectant management
  • Newborn management
  • Renal outcomes urinary tract infection
  • Spina bifida
  • Spinal dysraphism
  • Urodynamics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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