Evidence that a mutation in the MLH1 3′-untranslated region confers a mutator phenotype and mismatch repair deficiency in patients with relapsed leukemia

Medicine & Life Sciences

• Turcot syndrome 92%
• DNA Mismatch Repair 74%
• 3' Untranslated Regions 64%
• Leukemia 51%
• Phenotype 37%
• Mutation 34%
• Genes 20%
• Messenger RNA 17%
• Firefly Luciferases 14%
• Microsatellite Instability 12%
• Hematologic Neoplasms 10%
• Reporter Genes 10%
• Methylation 9%
• Epigenomics 9%
• Nucleotides 8%
• Leukocytes 8%
• Down-Regulation 7%
• Neoplasms 6%
• Cell Line 6%
• Recurrence 5%

Chemical Compounds

• Mutagenic Agent 100%
• Mutation 52%
• Haematological 29%
• Marker 18%
• White 17%
• Reduction 9%