TY - JOUR
T1 - Essentials of macroscopic evaluation of specimens from gastrointestinal tract
AU - Vyas, Monika
AU - Karamchandani, Dipti M.
N1 - Publisher Copyright:
© Author(s) (or their employer(s)) 2024.
PY - 2024/2/19
Y1 - 2024/2/19
N2 - An astute macroscopic examination, coupled with correlating the gross findings with clinical indication and operative notes along with judicious, yet all pertinent sectioning for pathological examination is crucial for an accurate histopathological diagnosis, eventually leading to optimal patient care. This succinct review highlights the general concepts that lay the foundation of evaluating and grossing specimens from the luminal gastrointestinal (GI) tract. We also discuss the gross evaluation and sectioning of small therapeutic resections, along with a systematic approach and rationale when grossing and submitting histological sections from larger oncological resections from the luminal GI tract. Selected site-specific considerations, for example, grossing treated rectal and oesophageal cancers or taking sections from mucinous tumours of the appendix, among others, are also discussed.
AB - An astute macroscopic examination, coupled with correlating the gross findings with clinical indication and operative notes along with judicious, yet all pertinent sectioning for pathological examination is crucial for an accurate histopathological diagnosis, eventually leading to optimal patient care. This succinct review highlights the general concepts that lay the foundation of evaluating and grossing specimens from the luminal gastrointestinal (GI) tract. We also discuss the gross evaluation and sectioning of small therapeutic resections, along with a systematic approach and rationale when grossing and submitting histological sections from larger oncological resections from the luminal GI tract. Selected site-specific considerations, for example, grossing treated rectal and oesophageal cancers or taking sections from mucinous tumours of the appendix, among others, are also discussed.
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U2 - 10.1136/jcp-2023-208981
DO - 10.1136/jcp-2023-208981
M3 - Review article
C2 - 38373784
AN - SCOPUS:85185619073
SN - 0021-9746
VL - 77
SP - 169
EP - 176
JO - Journal of clinical pathology
JF - Journal of clinical pathology
IS - 3
ER -