@article{ebedc607b6c84e3f91e1e807b56a83b1,
title = "ERKs, extracellular signal-regulated MAP-2 kinases",
abstract = "A family of protein kinases, known alternatively as microtubule-associated protein-2/myelin basic protein kinases or extracellular signal-regulated kinases, is activated by numerous hormones, growth factors and other extracellular stimuli. At least two members of this family function as intermediate kinases in protein phosphorylation cascades. Their mechanisms of activation may involve autophosphorylation, which occurs on both threonine and tyrosine residues.",
author = "Cobb, {Melanie H.} and Robbins, {David J.} and Boulton, {Teri G.}",
note = "Funding Information: We would like to thank Natalie Ahn, Rony Seger and Edwin Krebs at the University of Washington (Seattle) for valuable discussions and sign&cant contributions to work reviewed here, George Yan-copoulos and others of Regeneron Pharmaceuticals, Inc. and Tom Gepert for valuable collaborations, and Jo Hicks for preparation of the manuscript. We also thank L Greene and H Tsao. J Haycock. T Gotoh and E Nishhida and collaborators. W Biggs and L Zipursky. T Jacobs and B Duerr, and J Ruderman for communicating work prior to publication. Work performed in this laboratory was supported by research grant DK34128 and Research Career Development Awxd DK01918 from the National Institutes of Heahh.",
year = "1991",
month = dec,
doi = "10.1016/0955-0674(91)90124-H",
language = "English (US)",
volume = "3",
pages = "1025--1032",
journal = "Current Opinion in Cell Biology",
issn = "0955-0674",
publisher = "Elsevier Limited",
number = "6",
}