Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

J. Capdevila, G. D. Snijder, J R Falck

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy-eicosatrienoic acids as reaction products and thus documented the presence of an NADPH-dependent arachidonic acid epoxygenase activity in rat adenohypophysis.

Original languageEnglish (US)
Pages (from-to)319-322
Number of pages4
JournalFEBS Letters
Issue number2
StatePublished - Dec 10 1984


  • Anterior pituitary
  • Arachidonic acid
  • Epoxyeicosatrienoic acid
  • Epoxygenase

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology


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