Ephective endocytosis

Michael M. Halford; Michael J. Chumley; Mark Henkemeyer

doi:10.1016/S1534-5807(03)00299-5

Ephective endocytosis

Michael M. Halford, Michael J. Chumley, Mark Henkemeyer

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.

Original language	English (US)
Pages (from-to)	536-537
Number of pages	2
Journal	Developmental cell
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/S1534-5807(03)00299-5
State	Published - Oct 1 2003

ASJC Scopus subject areas

Molecular Biology
Biochemistry, Genetics and Molecular Biology(all)
Developmental Biology
Cell Biology

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10.1016/S1534-5807(03)00299-5

Cite this

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title = "Ephective endocytosis",

abstract = "Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.",

author = "Halford, {Michael M.} and Chumley, {Michael J.} and Mark Henkemeyer",

year = "2003",

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T1 - Ephective endocytosis

AU - Halford, Michael M.

AU - Chumley, Michael J.

AU - Henkemeyer, Mark

PY - 2003/10/1

Y1 - 2003/10/1

N2 - Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.

AB - Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.

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UR - http://www.scopus.com/inward/citedby.url?scp=0141989900&partnerID=8YFLogxK

U2 - 10.1016/S1534-5807(03)00299-5

DO - 10.1016/S1534-5807(03)00299-5

M3 - Review article

C2 - 14536055

AN - SCOPUS:0141989900

SN - 1534-5807

VL - 5

SP - 536

EP - 537

JO - Developmental cell

JF - Developmental cell

IS - 4

ER -

Ephective endocytosis

Abstract

ASJC Scopus subject areas

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