Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine

C. Tilden Hagan, Yu Mi, Nicole M. Knape, Andrew Z. Wang

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Radiotherapy and immunotherapy are two key treatments for cancer. There is growing evidence that they are also synergistic, and combination treatments are being studied extensively in the clinical setting. In addition, there is emerging evidence that nanotechnology-enabled therapeutics can potentiate both radiotherapy and immunotherapy, in turn improving both treatments. This is an exciting new area of interdisciplinary science and has significant potential for major clinical impact. Some of the approaches in this area have already reached the clinical stage. In this review, we will discuss recent advances in the interface between radiotherapy, immunotherapy, and nanomedicine. We plan to review the many approaches to combine these three fields for cancer treatment.

Original languageEnglish (US)
Pages (from-to)2668-2678
Number of pages11
JournalBioconjugate Chemistry
Issue number12
StatePublished - Dec 16 2020
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering
  • Pharmacology
  • Pharmaceutical Science
  • Organic Chemistry


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