Energy Regulation: HIF MXIes It Up with the C-MYC Powerhouse

Patrick D. Sutphin, Amato J. Giaccia, Denise A. Chan

Research output: Contribution to journalShort surveypeer-review

18 Scopus citations


The phenomenon of aerobic glycolysis observed in cancer cells has remained unexplained. In the May 2007 issue of Cancer Cell, Zhang and colleagues determine that the hypoxia-inducible factor family of transcriptional factors regulate mitochondrial biogenesis through inhibition of C-MYC.

Original languageEnglish (US)
Pages (from-to)845-846
Number of pages2
JournalDevelopmental cell
Issue number6
StatePublished - Jun 5 2007

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology


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