Endoscopically guided spectral-domain OCT with double-balloon catheters

Wei Kang, Hui Wang, Yinsheng Pan, Michael W. Jenkins, Gerard A. Isenberg, Amitabh Chak, Matthew Atkinson, Deepak Agrawal, Zhilin Hu, Andrew M. Rollins

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Fourier-domain optical coherence tomography (OCT) and balloon-based catheters have furthered the potential of OCT as a real-time surveillance tool for Barrett's esophagus (BE). However, a balloon catheter, which expands the esophagus and centers the catheter, applies direct pressure on the esophagus. This may affect the tissue appearance and the ability to detect dysplasia in BE. To study this effect, we propose a doubleballoon catheter to allow imaging with and without balloon-tissue contact. A system design based on a spectral-domain OCT platform is reported and validated by acquisition of high quality, volumetric images of swine esophagus in vivo.

Original languageEnglish (US)
Pages (from-to)17364-17372
Number of pages9
JournalOptics Express
Issue number16
StatePublished - Aug 2 2010

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics


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