TY - JOUR
T1 - Endoscopic therapies for gastroesophageal reflux disease
AU - De Hoyos, Alberto
AU - Fernando, Hiran C.
PY - 2005/6/1
Y1 - 2005/6/1
N2 - Gastroesophageal reflux disease (GERD) is a chronic condition affecting over 7% of the US population. The primary objective of therapy is symptom relief, with secondary goals to heal esophagitis, prevent reflux-related complications, and maintain remission. There are several new endoscopic therapies (ETs) for treatment of GERD, generating considerable interest. An outpatient procedure, performed without an incision and general anesthesia, is attractive to patients and these therapies are being rapidly introduced, despite lack of long-term follow-up and randomized trials. In this article, the authors review endoscopic procedures, including technical aspects, mechanisms of action, safety, efficacy, and tolerability. Patient selection and relevant human studies are reviewed to clarify advantages and disadvantages of ET compared with conventional procedures.
AB - Gastroesophageal reflux disease (GERD) is a chronic condition affecting over 7% of the US population. The primary objective of therapy is symptom relief, with secondary goals to heal esophagitis, prevent reflux-related complications, and maintain remission. There are several new endoscopic therapies (ETs) for treatment of GERD, generating considerable interest. An outpatient procedure, performed without an incision and general anesthesia, is attractive to patients and these therapies are being rapidly introduced, despite lack of long-term follow-up and randomized trials. In this article, the authors review endoscopic procedures, including technical aspects, mechanisms of action, safety, efficacy, and tolerability. Patient selection and relevant human studies are reviewed to clarify advantages and disadvantages of ET compared with conventional procedures.
UR - http://www.scopus.com/inward/record.url?scp=20344401066&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20344401066&partnerID=8YFLogxK
U2 - 10.1016/j.suc.2005.01.017
DO - 10.1016/j.suc.2005.01.017
M3 - Review article
C2 - 15927644
AN - SCOPUS:20344401066
SN - 0039-6109
VL - 85
SP - 465
EP - 481
JO - Surgical Clinics of North America
JF - Surgical Clinics of North America
IS - 3
ER -