Endoscopic therapies for gastroesophageal reflux disease

Alberto De Hoyos, Hiran C. Fernando

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Gastroesophageal reflux disease (GERD) is a chronic condition affecting over 7% of the US population. The primary objective of therapy is symptom relief, with secondary goals to heal esophagitis, prevent reflux-related complications, and maintain remission. There are several new endoscopic therapies (ETs) for treatment of GERD, generating considerable interest. An outpatient procedure, performed without an incision and general anesthesia, is attractive to patients and these therapies are being rapidly introduced, despite lack of long-term follow-up and randomized trials. In this article, the authors review endoscopic procedures, including technical aspects, mechanisms of action, safety, efficacy, and tolerability. Patient selection and relevant human studies are reviewed to clarify advantages and disadvantages of ET compared with conventional procedures.

Original languageEnglish (US)
Pages (from-to)465-481
Number of pages17
JournalSurgical Clinics of North America
Issue number3
StatePublished - Jun 1 2005

ASJC Scopus subject areas

  • Surgery


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