Endomicroscopy in Barrett's Esophagus

Kerry B. Dunbar

doi:10.1016/j.giec.2013.03.003

Endomicroscopy in Barrett's Esophagus

Kerry B. Dunbar

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

Barrett's esophagus has been a focus of confocal laser endomicroscopy (CLE) research. There are two CLE systems available, one probe-based and the other with a microscope embedded in the tip of an endoscope. Several CLE image classification systems are available. Studies suggest that CLE has good sensitivity, negative predictive value, and accuracy for detecting neoplasia, with good interobserver agreement using the CLE image classification systems. Larger, multicenter studies have been completed evaluating the impact of CLE on treatment of patients with BE. Future developments may include more specific contrast agents and new types of endomicroscopes.

Original language	English (US)
Pages (from-to)	565-579
Number of pages	15
Journal	Gastrointestinal Endoscopy Clinics of North America
Volume	23
Issue number	3
DOIs	https://doi.org/10.1016/j.giec.2013.03.003
State	Published - Jul 2013

Keywords

Barrett's esophagus
Barrett's neoplasia
Confocal endomicroscopy
Confocal laser endomicroscopy
Confocal microendoscopy
Esophageal adenocarcinoma
Esophageal imaging

ASJC Scopus subject areas

Gastroenterology

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10.1016/j.giec.2013.03.003

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title = "Endomicroscopy in Barrett's Esophagus",

abstract = "Barrett's esophagus has been a focus of confocal laser endomicroscopy (CLE) research. There are two CLE systems available, one probe-based and the other with a microscope embedded in the tip of an endoscope. Several CLE image classification systems are available. Studies suggest that CLE has good sensitivity, negative predictive value, and accuracy for detecting neoplasia, with good interobserver agreement using the CLE image classification systems. Larger, multicenter studies have been completed evaluating the impact of CLE on treatment of patients with BE. Future developments may include more specific contrast agents and new types of endomicroscopes.",

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AB - Barrett's esophagus has been a focus of confocal laser endomicroscopy (CLE) research. There are two CLE systems available, one probe-based and the other with a microscope embedded in the tip of an endoscope. Several CLE image classification systems are available. Studies suggest that CLE has good sensitivity, negative predictive value, and accuracy for detecting neoplasia, with good interobserver agreement using the CLE image classification systems. Larger, multicenter studies have been completed evaluating the impact of CLE on treatment of patients with BE. Future developments may include more specific contrast agents and new types of endomicroscopes.

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KW - Confocal laser endomicroscopy

KW - Confocal microendoscopy

KW - Esophageal adenocarcinoma

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Endomicroscopy in Barrett's Esophagus

Abstract

Keywords

ASJC Scopus subject areas

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