Efficient processing of laser speckle contrast images

W. James Tom, Adrien Ponticorvo, Andrew K. Dunn

Research output: Contribution to journalArticlepeer-review

68 Scopus citations


Though laser speckle contrast imaging enables the measurement of scattering particle dynamics with high temporal resolution, the subsequent processing has previously been much slower. In prior studies, generating a laser speckle contrast image required about 1 s to process a raw image potentially collected in 10 ms or less. In this paper, novel algorithms are described which are demonstrated to convert 291 raw images per second to laser speckle contrast images and as many as 410 laser speckle contrast images per second to relative correlation time images. As long as image processing occurs during image acquisition, these algorithms render processing time irrelevant in most circumstances and enable real-time imaging of blood flow dynamics.

Original languageEnglish (US)
Article number4520154
Pages (from-to)1728-1738
Number of pages11
JournalIEEE Transactions on Medical Imaging
Issue number12
StatePublished - Dec 2008
Externally publishedYes


  • Biomedical image processing
  • Blood flow
  • Blood vessels
  • Optical imaging
  • Speckle

ASJC Scopus subject areas

  • Software
  • Radiological and Ultrasound Technology
  • Computer Science Applications
  • Electrical and Electronic Engineering


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