Seventy-five per cent of fasting children are at risk for the development of pneumonitis following pulmonary aspiration of gastric contents: that is, the gastric fluid pH is less than 2.5 and the gastric fluid volume is greater than 0.4 ml·kg-1. Although metoclopramide and ranitidine increase the gastric fluid pH and decrease the fluid volume in adults, similar data in children are unavailable. Therefore, we compared the effectiveness of these drugs in fasting children undergoing elective surgery.
|Canadian Journal of Anaesthesia
|Published - Jan 1 1988
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine