Abstract
Cytoplasmic RNA was isolated from cells cultured with LPS and LPS plus a T cell-derived supernatant (SN) (PK 7.1) containing B cell differentiation factors. The steady state levels of isotype-specific mRNA were assessed by Northern blot analysis with γ-specific C(H)3 probes. It was demonstrated that the SN induces an increase in the level of mRNA for γ1 and a concomitant decrease in the levels of mRNA for γ2b and γ3.
Original language | English (US) |
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Pages (from-to) | 3049-3051 |
Number of pages | 3 |
Journal | Journal of Immunology |
Volume | 131 |
Issue number | 6 |
State | Published - 1983 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology