@article{4199f1f827964013a6e5213fafec14e7,
title = "Effect of plasma free fatty acids on plasma glucagon and serum insulin concentrations",
abstract = "The acute elevation of plasma free fatty acids to levels found during prolonged starvation by means of infusion of a triglyceride emulsion plus heparin in 5 dogs was associated with a 40 per cent decrease in plasma glucagon and a 33 per cent increase in serum insulin. This inhibitory feedback of free fatty acid on glucagon secretion and stimulatory feedback on insulin secretion very likely contribute to the smooth transition from carbohydrate to fat metabolism characteristic of prolonged starvation without the danger of progressive ketoacidosis.",
author = "Madison, {Leonard L.} and Seyffert, {Willis A.} and Unger, {Roger H} and Barbara Barker",
note = "Funding Information: From the Department of Internal Medicine, Univrrsity vf Texas Sorrthwestern Medical School at LIaRas, Dallas, Texus. This work was supported by a U. S. Public Health Service grant (AM-4236) from the National Institute of Arthritis and Metabolic Diseases, Rcthcsda, ,%faryland. Received for pnblication August 21, 1.967. LEONAHI) L,. MADISON, M.D.: Professor of internal Medicine, University of Texas South-western Medical School at Dallas. WILLI> .4. SEYFFERT, JR., M.D.: Postdoctoral Research Fellow, Department of Internal Medicine, University of Texas Southwestern Medical School at Dalhts. HOCER H. UNGER, M.D.: Director of Research, I{\textquoteright}eterans Administration Hospitul. Dallas, Texas. BARBARA BARKER: Research Technician, Department of Internal Medicine. lJniversit!y of Texas Southwestern Medical School at 13alla.s.",
year = "1968",
month = apr,
doi = "10.1016/0026-0495(68)90097-8",
language = "English (US)",
volume = "17",
pages = "301--304",
journal = "Metabolism",
issn = "0026-0495",
publisher = "W.B. Saunders Ltd",
number = "4",
}