Dysmorphic villi mimicking partial mole in a case with del(18)(q21)

Dinesh Rakheja; Kathleen S Wilson; Beverly B. Rogers

doi:10.1007/s10024-004-2022-8

Dysmorphic villi mimicking partial mole in a case with del(18)(q21)

Dinesh Rakheja, Kathleen S Wilson, Beverly B. Rogers

Research output: Contribution to journal › Article › peer-review

Abstract

In this article, we report the histopathologic findings in a placenta from an early second trimester abortion. The placental villi showed prominent scalloping with many intravillous trophoblastic pseudoinclusions and mild trophoblastic hyperplasia, mimicking the morphology of partial hydatidiform mole. The placental karyotype was 46,XY,del(18)(q21). These histopathologic changes have been previously described in numerical chromosomal aberrations like triploidy, tetraploidy, and trisomies, but not in structural chromosomal abnormalities.

Original language	English (US)
Pages (from-to)	546-548
Number of pages	3
Journal	Pediatric and Developmental Pathology
Volume	7
Issue number	5
DOIs	https://doi.org/10.1007/s10024-004-2022-8
State	Published - Nov 2004

Keywords

Chromosomal deletion
Dysmorphic villi
Partial hydatidiform mole

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Pathology and Forensic Medicine

Access to Document

10.1007/s10024-004-2022-8

Cite this

@article{0bd2b69ea9ba49e8abeb4659e0e93e46,

title = "Dysmorphic villi mimicking partial mole in a case with del(18)(q21)",

abstract = "In this article, we report the histopathologic findings in a placenta from an early second trimester abortion. The placental villi showed prominent scalloping with many intravillous trophoblastic pseudoinclusions and mild trophoblastic hyperplasia, mimicking the morphology of partial hydatidiform mole. The placental karyotype was 46,XY,del(18)(q21). These histopathologic changes have been previously described in numerical chromosomal aberrations like triploidy, tetraploidy, and trisomies, but not in structural chromosomal abnormalities.",

keywords = "Chromosomal deletion, Dysmorphic villi, Partial hydatidiform mole",

author = "Dinesh Rakheja and Wilson, {Kathleen S} and Rogers, {Beverly B.}",

year = "2004",

month = nov,

doi = "10.1007/s10024-004-2022-8",

language = "English (US)",

volume = "7",

pages = "546--548",

journal = "Pediatric and Developmental Pathology",

issn = "1093-5266",

publisher = "Society for Pediatric Pathology",

number = "5",

}

TY - JOUR

T1 - Dysmorphic villi mimicking partial mole in a case with del(18)(q21)

AU - Rakheja, Dinesh

AU - Wilson, Kathleen S

AU - Rogers, Beverly B.

PY - 2004/11

Y1 - 2004/11

N2 - In this article, we report the histopathologic findings in a placenta from an early second trimester abortion. The placental villi showed prominent scalloping with many intravillous trophoblastic pseudoinclusions and mild trophoblastic hyperplasia, mimicking the morphology of partial hydatidiform mole. The placental karyotype was 46,XY,del(18)(q21). These histopathologic changes have been previously described in numerical chromosomal aberrations like triploidy, tetraploidy, and trisomies, but not in structural chromosomal abnormalities.

AB - In this article, we report the histopathologic findings in a placenta from an early second trimester abortion. The placental villi showed prominent scalloping with many intravillous trophoblastic pseudoinclusions and mild trophoblastic hyperplasia, mimicking the morphology of partial hydatidiform mole. The placental karyotype was 46,XY,del(18)(q21). These histopathologic changes have been previously described in numerical chromosomal aberrations like triploidy, tetraploidy, and trisomies, but not in structural chromosomal abnormalities.

KW - Chromosomal deletion

KW - Dysmorphic villi

KW - Partial hydatidiform mole

UR - http://www.scopus.com/inward/record.url?scp=15244339142&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15244339142&partnerID=8YFLogxK

U2 - 10.1007/s10024-004-2022-8

DO - 10.1007/s10024-004-2022-8

M3 - Article

C2 - 15547780

AN - SCOPUS:15244339142

SN - 1093-5266

VL - 7

SP - 546

EP - 548

JO - Pediatric and Developmental Pathology

JF - Pediatric and Developmental Pathology

IS - 5

ER -

Dysmorphic villi mimicking partial mole in a case with del(18)(q21)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this