Drivers of EMT and immune evasion

Rolf A. Brekken; Katarzyna Wnuk-Lipinska

doi:10.1007/978-3-319-39147-2_9

Drivers of EMT and immune evasion

Rolf A. Brekken, Katarzyna Wnuk-Lipinska

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

The heterogeneity of tumor cells and the complexity of the surrounding microenvironment make the process of predicting patient outcome and selection of the most suitable treatment regimen very difficult. Over the past decades, many biomarkers have been evaluated for prognostic value. The advent of immune therapy as a frontline treatment for some cancers has moved immune phenotyping into the forefront of biomarker and predictive marker research. Here, we review some of the regulatory mechanisms of the host immune response and epithelial plasticity and highlight their potential as biomarkers of the hallmark of immune evasion.

Original language	English (US)
Title of host publication	Biomarkers of the Tumor Microenvironment
Subtitle of host publication	Basic Studies and Practical Applications
Publisher	Springer International Publishing
Pages	221-239
Number of pages	19
ISBN (Electronic)	9783319391472
ISBN (Print)	9783319391458
DOIs	https://doi.org/10.1007/978-3-319-39147-2_9
State	Published - Aug 2 2017

Keywords

EMT
Immunosuppression
Inflammation
Phosphatidylserine
TAM receptors

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-319-39147-2_9

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KW - Inflammation

KW - Phosphatidylserine

KW - TAM receptors

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ER -

Drivers of EMT and immune evasion

Abstract

Keywords

ASJC Scopus subject areas

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