TY - JOUR
T1 - Dobutamine echocardiography in predicting improvement in global left ventricular systolic function after coronary bypass or angioplasty in patients with healed myocardial infarcts
AU - Meluzin, Jaroslav
AU - Cigarroa, Carlos G.
AU - Brickner, M. Elizabeth
AU - Cerny, Jan
AU - Spinarova, Lenka
AU - Frelich, Milan
AU - Stetka, Frantisek
AU - Groch, Ladislav
AU - Grayburn, Paul A.
PY - 1995/11/1
Y1 - 1995/11/1
N2 - The aim of this study was to determine whether low-dose dobutamine ecnocardiography (DE) could predict quantitative improvement in global left ventricular (LV) systolic function after coronary revascularization. Low-dose DE was performed in 71 consecutive patients with coronary artery disease and LV dysfunction. Successful coronary bypass surgery or angioplasty was performed in 44 patients, 37 of whom had a resting echocardiogram 1 to 3 months afterward. Group A consisted of 20 patients with contractile reserve during DE, and group B consisted of 17 patients without contractile reserve. As expected, regional wall motion score index (mean ± SD) improved in group A (1.62 ± 0.39 to 1.38 ± 0.31, p < 0.01) but not group B (1.56 ± 0.42 to 1.57 ± 0.41, p = NS). In addition, LV ejection fraction (LVEF) improved after bypass surgery or angio plasty in group A (38 ± 5% to 42 ± 5%, p < 0.01), but not in group B (38 ± 7% to 39 ± 8%, p = NS). In group A, a significant linear correlation was observed between the number of segments with contractile reserve and the improvement in LVEF (r = 0.91, p < 0.0001). A good correlation also existed between the improvement in regional wall motion score index during dobutamine infusion and the improvement in LVEF after bypass surgery or angioplasty (r = 0.90, p < 0.0001). In conclusion, low-dose DE can be used to predict quantitative improvement in global LV systolic function after coronary bypass or angioplasty.
AB - The aim of this study was to determine whether low-dose dobutamine ecnocardiography (DE) could predict quantitative improvement in global left ventricular (LV) systolic function after coronary revascularization. Low-dose DE was performed in 71 consecutive patients with coronary artery disease and LV dysfunction. Successful coronary bypass surgery or angioplasty was performed in 44 patients, 37 of whom had a resting echocardiogram 1 to 3 months afterward. Group A consisted of 20 patients with contractile reserve during DE, and group B consisted of 17 patients without contractile reserve. As expected, regional wall motion score index (mean ± SD) improved in group A (1.62 ± 0.39 to 1.38 ± 0.31, p < 0.01) but not group B (1.56 ± 0.42 to 1.57 ± 0.41, p = NS). In addition, LV ejection fraction (LVEF) improved after bypass surgery or angio plasty in group A (38 ± 5% to 42 ± 5%, p < 0.01), but not in group B (38 ± 7% to 39 ± 8%, p = NS). In group A, a significant linear correlation was observed between the number of segments with contractile reserve and the improvement in LVEF (r = 0.91, p < 0.0001). A good correlation also existed between the improvement in regional wall motion score index during dobutamine infusion and the improvement in LVEF after bypass surgery or angioplasty (r = 0.90, p < 0.0001). In conclusion, low-dose DE can be used to predict quantitative improvement in global LV systolic function after coronary bypass or angioplasty.
UR - http://www.scopus.com/inward/record.url?scp=0028798945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028798945&partnerID=8YFLogxK
U2 - 10.1016/S0002-9149(99)80253-7
DO - 10.1016/S0002-9149(99)80253-7
M3 - Article
C2 - 7484824
AN - SCOPUS:0028798945
SN - 0002-9149
VL - 76
SP - 877
EP - 880
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 12
ER -