Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells?

Eric G. Pamer; Michael J. Bevan; Kirsten Fischer Lindahl

doi:10.1016/0966-842X(93)90023-K

Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells?

Eric G. Pamer, Michael J. Bevan, Kirsten Fischer Lindahl

Immunology

Research output: Contribution to journal › Comment/debate › peer-review

23 Scopus citations

Abstract

Immune responses to bacterial antigens that appear unrestricted by the MHC may involve oligomorphic MHC class Ib H-2M3, which binds N-formylated peptides and presents a Listeria peptide to cytotoxic T cells from infected mice. Lack of polymorphism makes these molecules a promising target for peptide vaccines.

Original language	English (US)
Pages (from-to)	35-38
Number of pages	4
Journal	Trends in Microbiology
Volume	1
Issue number	1
DOIs	https://doi.org/10.1016/0966-842X(93)90023-K
State	Published - Apr 1993

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

Access to Document

10.1016/0966-842X(93)90023-K

Cite this

@article{a3497818c1c84ff7bb04b4ae91a31479,

title = "Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells?",

abstract = "Immune responses to bacterial antigens that appear unrestricted by the MHC may involve oligomorphic MHC class Ib H-2M3, which binds N-formylated peptides and presents a Listeria peptide to cytotoxic T cells from infected mice. Lack of polymorphism makes these molecules a promising target for peptide vaccines.",

author = "Pamer, {Eric G.} and Bevan, {Michael J.} and Lindahl, {Kirsten Fischer}",

year = "1993",

month = apr,

doi = "10.1016/0966-842X(93)90023-K",

language = "English (US)",

volume = "1",

pages = "35--38",

journal = "Trends in Microbiology",

issn = "0966-842X",