Differences in optic discs in low-tension glaucoma patients with relatively low or high pressures

Xiao Hong Wang, William C. Stewart, Galin J. Jackson

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


We evaluated the differences in the optic nerve head in patients with chronic open-angle glaucoma (HTG) and those with low-tension glaucoma with either relatively high (between 16 and 21 mmHg [LTGH]) or low (≤ 15 mmHg [LTGL]) intraocular pressures. We included 36 patients in this study. We found that LTGL patients had a significantly greater mean area of peripapillary atrophy inferior to the optic disc (0.65 ± 0.38 mm2) than LTGH (0.40 ± 0.38 mm2) or HTG (0.34 ± 0.25 mm2) patients (p < 0.005). No significant difference was found between groups for the area of the neural rim, optic disc, cup/pallor discrepancy, or peripapillary halo, or in the diameter of the largest artery or vein in the inferior and superior peripapillary area. This study raises the question of whether a separate mechanism of damage could exist at the optic disc in patients whose intraocular pressure is ≤ 15 mmHg because of a greater extent of peripapillary atrophy than in patients with higher intraocular pressures.

Original languageEnglish (US)
Pages (from-to)364-367
Number of pages4
JournalActa Ophthalmologica Scandinavica
Issue number4
StatePublished - Aug 1996


  • Chronic open-angle glaucoma
  • Intraocular pressure
  • Low-tension glaucoma
  • Optic disc
  • Peripapillary atrophy

ASJC Scopus subject areas

  • Ophthalmology


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