Diagnosis and management of FVII deficiency

Ruchika Sharma, Bryce A. Kerlin

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Factor VII is a clotting factor produced by the liver that interacts with tissue factor to initiate blood coagulation. Deficiency of factor VII can present with variable bleeding symptoms. There is a lack of correlation between clinical phenotypes and FVII coagulant activity. It is inherited in an autosomal recessive fashion. Outcomes and management options are discussed in context of a case presentation.

Original languageEnglish (US)
Title of host publicationPediatric Bleeding Disorders
Subtitle of host publicationA Clinical Casebook
PublisherSpringer International Publishing
Number of pages6
ISBN (Electronic)9783030316617
ISBN (Print)9783030316600
StatePublished - Jan 1 2020
Externally publishedYes


  • Clotting factor
  • Factor VII deficiency
  • Recombinant factor VII
  • Tissue factor

ASJC Scopus subject areas

  • Medicine(all)


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