Diagnosis and management of FVII deficiency

Ruchika Sharma; Bryce A. Kerlin

doi:10.1007/978-3-030-31661-7_6

Diagnosis and management of FVII deficiency

Ruchika Sharma, Bryce A. Kerlin

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Factor VII is a clotting factor produced by the liver that interacts with tissue factor to initiate blood coagulation. Deficiency of factor VII can present with variable bleeding symptoms. There is a lack of correlation between clinical phenotypes and FVII coagulant activity. It is inherited in an autosomal recessive fashion. Outcomes and management options are discussed in context of a case presentation.

Original language	English (US)
Title of host publication	Pediatric Bleeding Disorders
Subtitle of host publication	A Clinical Casebook
Publisher	Springer International Publishing
Pages	59-64
Number of pages	6
ISBN (Electronic)	9783030316617
ISBN (Print)	9783030316600
DOIs	https://doi.org/10.1007/978-3-030-31661-7_6
State	Published - Jan 1 2020
Externally published	Yes

Keywords

Clotting factor
Factor VII deficiency
Recombinant factor VII
Tissue factor

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1007/978-3-030-31661-7_6

Cite this

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AB - Factor VII is a clotting factor produced by the liver that interacts with tissue factor to initiate blood coagulation. Deficiency of factor VII can present with variable bleeding symptoms. There is a lack of correlation between clinical phenotypes and FVII coagulant activity. It is inherited in an autosomal recessive fashion. Outcomes and management options are discussed in context of a case presentation.

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KW - Recombinant factor VII

KW - Tissue factor

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Diagnosis and management of FVII deficiency

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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