Determining cardiac fiber orientation using FSL and registered ultrasound/DTI volumes

James Dormer, Xulei Qin, Ming Shen, Silun Wang, Xiaodong Zhang, Rong Jiang, Mary B. Wagner, Baowei Fei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations


Accurate extraction of cardiac fiber orientation from diffusion tensor imaging is important for determining heart structure and function. However, the acquisition of magnetic resonance (MR) diffusion tensor images is costly and time consuming. By comparison, cardiac ultrasound imaging is rapid and relatively inexpensive, but it lacks the capability to directly measure fiber orientations. In order to create a detailed heart model from ultrasound data, a three-dimensional (3D) diffusion tensor imaging (DTI) with known fiber orientations can be registered to an ultrasound volume through a geometric mask. After registration, the cardiac orientations from the template DTI can be mapped to the heart using a deformable transformation field. This process depends heavily on accurate fiber orientation extraction from the DTI. In this study, we use the FMRIB Software Library (FSL) to determine cardiac fiber orientations in diffusion weighted images. For the registration between ultrasound and MRI volumes, we achieved an average Dice similarity coefficient (DSC) of 81.6±2.1%. For the estimation of fiber orientations from the proposed method, we achieved an acute angle error (AAE) of 22.7±3.1° as compared to the direct measurements from DTI. This work provides a new approach to generate cardiac fiber orientation that may be used for many cardiac applications.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2016
Subtitle of host publicationUltrasonic Imaging and Tomography
EditorsBrecht Heyde, Brecht Heyde, Neb Duric
ISBN (Electronic)9781510600256
StatePublished - 2016
Externally publishedYes
EventMedical Imaging 2016: Ultrasonic Imaging and Tomography - San Diego, United States
Duration: Feb 28 2016Feb 29 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMedical Imaging 2016: Ultrasonic Imaging and Tomography
Country/TerritoryUnited States
CitySan Diego

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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