Design and implementation of the resuscitation outcomes consortium pragmatic airway resuscitation trial (PART)

Henry E. Wang, David K. Prince, Shannon W. Stephens, Heather Herren, Mohamud Daya, Neal Richmond, Jestin Carlson, Craig Warden, M. Riccardo Colella, Ashley Brienza, Tom P. Aufderheide, Ahamed H. Idris, Robert Schmicker, Susanne May, Graham Nichol

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Airway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.

Original languageEnglish (US)
Pages (from-to)57-64
Number of pages8
StatePublished - Apr 1 2016


  • Airway management
  • Cardiopulmonary arrest
  • Clinical trials
  • Emergency medical services
  • Intubation (intratracheal)
  • Resuscitation

ASJC Scopus subject areas

  • Emergency Medicine
  • Emergency
  • Cardiology and Cardiovascular Medicine


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