@article{9baac20990f8496d9d92c9cedf8aaa33,
title = "Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression",
abstract = "Depressive symptoms, assessed using a self-report type of questionnaire, have been associated with poor outcomes in dialysis patients. Here we determined if depressive disorders diagnosed by physicians are also associated with such outcomes. Ninety-eight consecutive patients on chronic hemodialysis underwent the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders administered by a physician. Depression was diagnosed in about a quarter of the patients. Associations adjusted for age, gender, race, time on dialysis and co-morbidity were determined using survival analysis. Using time to event (death or hospitalization) models of analysis the hazard ratios were 2.11 and 2.07 in unadjusted and adjusted models respectively. The finding of poor outcome using a formal structured physician interview suggests that a prospective study is needed to determine whether treatment of depression affects clinical outcomes.",
keywords = "Depression, Dialysis, Hospitalization, Mortality",
author = "Hedayati, {S. Susan} and Bosworth, {Hayden B.} and Briley, {Libbie P.} and Sloane, {Richard J.} and Pieper, {Carl F.} and Kimmel, {Paul L.} and Szczech, {Lynda A.}",
note = "Funding Information: The views expressed in this article are those of the authors and do not necessarily represent the views of the Department of Veterans Affairs. Dr Hedayati's research was supported by a fellowship grant from the Agency for Health Care, Research and Quality, John A. Hartford Foundation Grant 990339, and Claude D. Pepper Older Americans Independence Center Grant AG11268. Dr Pieper was supported by the same Claude D. Pepper Older Americans Independence Center Grant (AG11268). Dr Szczech's work was supported by grant DK02724-01A1 from the National Institutes of Health. Dr Bosworth's work was supported by the Department of Veterans Affairs, Veterans Health Administration, Health Services Research and Development, investigator initiative grant 20-034, a grant from the National Heart, Lung and Blood Institutes (R01 HL070713), and Established Investigator Award from the American Medical Association. This study was presented in abstract form at the American Society of Nephrology 38th Annual Meeting in Philadelphia, PA, USA, November 2005. ",
year = "2008",
month = oct,
doi = "10.1038/ki.2008.311",
language = "English (US)",
volume = "74",
pages = "930--936",
journal = "Kidney international",
issn = "0085-2538",
publisher = "Nature Publishing Group",
number = "7",
}