De-implementation of cervical cancer screening before age 21

Michelle I. Silver, Melissa L. Anderson, Elisabeth F. Beaber, Jennifer S. Haas, Sarah Kobrin, Gaia Pocobelli, Celette Sugg Skinner, Jasmin A. Tiro, Aruna Kamineni

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


In 2012, United States consensus guidelines were modified to recommend that cervical cancer screening not begin before age 21 and, since 2014, the Health Effectiveness Data and Information Set (HEDIS), a health plan quality measurement too, has included a measure for non-recommended cervical cancer screening among females ages 16–20. Our goal was to describe prevalence over time of cervical cancer screening before age 21 following the 2012 guideline change, and provide information to help understand how rapidly new guidelines may be disseminated and implemented into clinical practice. We used longitudinal clinical and administrative data from three diverse healthcare systems in the Population-based Research to Optimize the Screening Process (PROSPR II) consortium to examine annual trends in screening before age 21. We identified 55,316 average-risk, screening-eligible females ages 18–20 between 2011 and 2017. For each calendar year, we estimated the proportion of females who received a Papanicolaou (Pap) test. We observed a steady decline in the proportion of females under age 21 who received a Pap test, from an average of 8.3% in 2011 to <1% in 2017 across the sites. The observed steady decline suggests growing adherence to the 2012 consensus guidelines. This trend was consistent across diverse geographic regions, healthcare systems, and patient populations, strengthening the generalizability of the results; however, since we only had 1–2 years of study data prior to the consensus guidelines, we cannot discern whether screening under age 21 was already in decline. Nonetheless, these results provide data to compare with other guideline changes to de-implement non-recommended screening practices.

Original languageEnglish (US)
Article number106815
JournalPreventive Medicine
StatePublished - Dec 2021

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health


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