Daryamide Analogues from a Marine-Derived Streptomyces species

Peng Fu, Scott La, John B. MacMillan

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Three new cyclohexene amine derivatives, daryamides D-F (1-3), a new arylamine derivative, carpatamide D (4), and a new ornithine lactamization derivative, ornilactam A (5), were isolated from the marine-derived Streptomyces strain SNE-011. Their structures, including absolute configurations, were elucidated on the basis of spectroscopic analysis and chemical methods. The carpatamide skeleton could be considered as the biosynthetic precursor of the daryamides.

Original languageEnglish (US)
Pages (from-to)1096-1101
Number of pages6
JournalJournal of Natural Products
Issue number4
StatePublished - Apr 28 2017

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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