TY - JOUR
T1 - Daryamide Analogues from a Marine-Derived Streptomyces species
AU - Fu, Peng
AU - La, Scott
AU - MacMillan, John B.
N1 - Funding Information:
We acknowledge the following grants for funding this project: Welch Foundation I-1689 and NIH R01 CA149833. J.B.M. is a Chilton/Bell Foundation Endowed Scholar.
Publisher Copyright:
© 2017 The American Chemical Society and American Society of Pharmacognosy.
PY - 2017/4/28
Y1 - 2017/4/28
N2 - Three new cyclohexene amine derivatives, daryamides D-F (1-3), a new arylamine derivative, carpatamide D (4), and a new ornithine lactamization derivative, ornilactam A (5), were isolated from the marine-derived Streptomyces strain SNE-011. Their structures, including absolute configurations, were elucidated on the basis of spectroscopic analysis and chemical methods. The carpatamide skeleton could be considered as the biosynthetic precursor of the daryamides.
AB - Three new cyclohexene amine derivatives, daryamides D-F (1-3), a new arylamine derivative, carpatamide D (4), and a new ornithine lactamization derivative, ornilactam A (5), were isolated from the marine-derived Streptomyces strain SNE-011. Their structures, including absolute configurations, were elucidated on the basis of spectroscopic analysis and chemical methods. The carpatamide skeleton could be considered as the biosynthetic precursor of the daryamides.
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U2 - 10.1021/acs.jnatprod.7b00011
DO - 10.1021/acs.jnatprod.7b00011
M3 - Article
C2 - 28225277
AN - SCOPUS:85018407875
SN - 0163-3864
VL - 80
SP - 1096
EP - 1101
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 4
ER -