CyberArc: A non-coplanar-arc optimization algorithm for CyberKnife

Vasant Kearney, Joey P. Cheung, Christopher McGuinness, Timothy D. Solberg

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


The goal of this study is to demonstrate the feasibility of a novel non-coplanar-arc optimization algorithm (CyberArc). This method aims to reduce the delivery time of conventional CyberKnife treatments by allowing for continuous beam delivery. CyberArc uses a 4 step optimization strategy, in which nodes, beams, and collimator sizes are determined, source trajectories are calculated, intermediate radiation models are generated, and final monitor units are calculated, for the continuous radiation source model. The dosimetric results as well as the time reduction factors for CyberArc are presented for 7 prostate and 2 brain cases. The dosimetric quality of the CyberArc plans are evaluated using conformity index, heterogeneity index, local confined normalized-mutual-information, and various clinically relevant dosimetric parameters. The results indicate that the CyberArc algorithm dramatically reduces the treatment time of CyberKnife plans while simultaneously preserving the dosimetric quality of the original plans.

Original languageEnglish (US)
Pages (from-to)5777-5789
Number of pages13
JournalPhysics in Medicine and Biology
Issue number14
StatePublished - Jun 26 2017


  • arc therapy
  • CyberKnife
  • non-coplaner
  • optimization

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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