Cutaneous Crohn's disease mimicking Melkersson-Rosenthal syndrome: Treatment with methotrexate

Viseslav Tonkovic-Capin, S. S. Galbraith, R. S. Rogers, D. G. Binion, K. B. Yancey

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


A woman with a 5-year history of unilateral orofacial granulomatosis required repeated evaluations (including sequential colonoscopies) to establish the diagnosis of cutaneous Crohn's disease, a condition that proved responsive to low doses of oral methotrexate administered weekly. To our knowledge this is the first report describing the use of methotrexate for treatment of orofacial granulomatosis caused by underlying Crohn's disease.

Original languageEnglish (US)
Pages (from-to)449-452
Number of pages4
JournalJournal of the European Academy of Dermatology and Venereology
Issue number4
StatePublished - Apr 1 2006


  • Cheilitis granulomatosa
  • Crohn's disease
  • Melkersson-Rosenthal syndrome
  • Methotrexate
  • Orofacial granulomatosis

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases


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