Current and emerging strategies in the management of Crohn's disease

Charles Randall, John Vizuete, Gregg Wendorf, Balaji Ayyar, Gregory Constantine

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Diarrhoea is a common manifestation of Crohn's disease (CD). We advocate an evidence-based approach to treat the underlying disease and reduce symptoms. This article reviews disease grading systems, current concepts in medical therapy, and other treatments that may become available in the future. While some drug classes (e.g. salicylates, immunomodulators) have been studied for many decades, newer approaches including anti-TNF monoclonal antibodies (biologics), and gut selective agents are changing the paradigm we use to treat this debilitating condition.

Original languageEnglish (US)
Pages (from-to)601-610
Number of pages10
JournalBest Practice and Research: Clinical Gastroenterology
Issue number5
StatePublished - Oct 2012
Externally publishedYes


  • Crohn's disease
  • Diarrhoea
  • IBD

ASJC Scopus subject areas

  • Gastroenterology


Dive into the research topics of 'Current and emerging strategies in the management of Crohn's disease'. Together they form a unique fingerprint.

Cite this