Current advances in local protein synthesis and synaptic plasticity.

Research output: Contribution to journalReview articlepeer-review

131 Scopus citations


Local or dendritic protein synthesis is required for long-term functional synaptic change, such as long-term potentiation (LTP) and long-term depression (LTD). LTP and LTD both rely on similar signal transduction cascades, which regulate translation initiation. Current research indicates that the specificity by which new proteins participate in either LTP or LTD may be determined in part by specific RNA-binding proteins as well as activity-dependent capture.

Original languageEnglish (US)
Pages (from-to)7147-7150
Number of pages4
JournalThe Journal of neuroscience : the official journal of the Society for Neuroscience
Issue number27
StatePublished - Jul 5 2006

ASJC Scopus subject areas

  • General Neuroscience


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