Corneal oxygen deficiency

Desmond Fonn, Deborah Sweeney, Brien A. Holden, Harrison D Cavanagh

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


Objectives. To compare the ocular effects of low Dk hydrogel and high Dk silicone hydrogel contact lenses. Methods. A review of recent literature was conducted to determine the effects of wearing low and high Dk soft lenses on corneal swelling, vascular response, refractive error and the corneal epithelium. Results. High Dk silicone hydrogel contact lenses became available for research and clinical practice almost 10 and 5 years ago respectively. During that time many studies have been conducted and it has been demonstrated repeatedly how much improvement there has been to the physiological response of the eye particularly when wearing the lenses on an overnight basis. Conclusions. Although silicone hydrogels only constitute about 2% of current wearers, their positive effects on the eye compared with low Dk hydrogel lenses should make them the most dominant lenses in the near future.

Original languageEnglish (US)
Pages (from-to)23-27
Number of pages5
JournalEye and Contact Lens
Issue number1
StatePublished - Jan 1 2005


  • Bacterial binding
  • Corneal oxygen deficiency
  • Corneal swelling
  • Epithelial microcysts
  • Hypoxia
  • Increased myopia
  • Limbal hyperemia
  • Neovascularization

ASJC Scopus subject areas

  • Ophthalmology


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