Core concepts and treatment of metabolic acidosis

Michael R. Wiederkehr; Orson W. Moe

doi:10.1007/978-1-4614-3770-3_8

Core concepts and treatment of metabolic acidosis

Michael R. Wiederkehr, Orson W. Moe

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

Acid-base homeostasis constitutes one of the most fundamental biologic processes vital to survival of all life-forms. Derangements acid-base balance can result from a variety of causes and can exert multiple effects on many organs. Metabolic acidosis is a state of excess accumulation of acid in the body due to excess production, reduced excretion, or a combination of both. In this chapter, we summarize some basic acid-base chemistry and biology for the clinician, highlights how to utilize simple laboratory findings to approach metabolic acidosis, and finally discuss the evidence that supports the various treatment protocols and controversies in metabolic acidosis.

Original language	English (US)
Title of host publication	Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance
Publisher	Springer US
Pages	235-274
Number of pages	40
ISBN (Electronic)	9781461437703
ISBN (Print)	1461437695, 9781461437697
DOIs	https://doi.org/10.1007/978-1-4614-3770-3_8
State	Published - Nov 1 2013

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-3770-3_8

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AB - Acid-base homeostasis constitutes one of the most fundamental biologic processes vital to survival of all life-forms. Derangements acid-base balance can result from a variety of causes and can exert multiple effects on many organs. Metabolic acidosis is a state of excess accumulation of acid in the body due to excess production, reduced excretion, or a combination of both. In this chapter, we summarize some basic acid-base chemistry and biology for the clinician, highlights how to utilize simple laboratory findings to approach metabolic acidosis, and finally discuss the evidence that supports the various treatment protocols and controversies in metabolic acidosis.

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Core concepts and treatment of metabolic acidosis

Abstract

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