Core concepts and treatment of metabolic acidosis

Michael R. Wiederkehr, Orson W. Moe

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Acid-base homeostasis constitutes one of the most fundamental biologic processes vital to survival of all life-forms. Derangements acid-base balance can result from a variety of causes and can exert multiple effects on many organs. Metabolic acidosis is a state of excess accumulation of acid in the body due to excess production, reduced excretion, or a combination of both. In this chapter, we summarize some basic acid-base chemistry and biology for the clinician, highlights how to utilize simple laboratory findings to approach metabolic acidosis, and finally discuss the evidence that supports the various treatment protocols and controversies in metabolic acidosis.

Original languageEnglish (US)
Title of host publicationCore Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance
PublisherSpringer US
Number of pages40
ISBN (Electronic)9781461437703
ISBN (Print)1461437695, 9781461437697
StatePublished - Nov 1 2013

ASJC Scopus subject areas

  • General Medicine


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