Abstract
(Chemical Equation Presented) HOMO-logous: The copper-mediated cycloaddition of alkynes with diazo carbonyl compounds to give pyrazoles is reminiscent of the copper-catalyzed cycloaddition of alkynes and azides. The formation of the copper acetylide is proposed to narrow the energy gap between the highest occupied molecular orbital (HOMO) of the alkyne and the lowest unoccupied molecular orbital (LUMO) of the diazo compound.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3242-3244 |
| Number of pages | 3 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 46 |
| Issue number | 18 |
| DOIs | |
| State | Published - 2007 |
Keywords
- Acetylides
- Copper
- Cycloaddition
- Diazo compounds
- Heterocycles
ASJC Scopus subject areas
- Catalysis
- General Chemistry