Convenient preparation of α-trimethylsilyloxy- and α-hydroxystannanes from aldehydes

Rama K. Bhatt, Jianhua Ye, J. R. Falck

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Aldehydes, but not ketones, are converted to α-hydroxystannanes via the corresponding silyl ethers in good to excellent yields by Bu4NCN catalyzed addition of Bu3SnSiMe3 and hydrolytic isolation. Modest asymmetric induction was observed using a chiral quaternary ammonium cyanide catalyst.

Original languageEnglish (US)
Pages (from-to)4081-4084
Number of pages4
JournalTetrahedron Letters
Issue number24
StatePublished - Jun 13 1994


  • chiral induction
  • stannylhydrin
  • tin
  • trimethyl(tributylstannyl)silane

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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