Continuous arteriovenous rewarming: Rapid reversal of hypothermia in critically Ill patients

L. M. Gentilello, R. A. Cobean, P. J. Offner, R. W. Soderberg, G. J. Jurkovich

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Hypothermia in critically ill patients can be difficult to treat with standard rewarming (SR) techniques. We developed a rewarming method that is significantly faster than SR. Percutaneously placed femoral arterial and venous catheters were connected to the inflow and outflow side of a countercurrent fluid warmer to create a fistula through the heating mechanism (CAVR). Over a 10-month period 34 hypothermic (temperature < 35°C) patients were treated. Eighteen received SR only; CAVR was added to SR in the remaining 16 patients. Both groups were similar in APACHE II, Injury Severity, and Acute Physiology scores, prewarming blood and fluid requirements, and incidence of coagulopathy. Hypothermia resolved in 39 minutes with CAVR vs. 3.23 hours with SR (p < 0.001). This was associated with an improved survival after moderately severe injury (p = 0.04), and a significant reduction in blood and fluid requirements, organ failures, and length of ICU stay.

Original languageEnglish (US)
Pages (from-to)316-327
Number of pages12
JournalJournal of Trauma - Injury, Infection and Critical Care
Issue number3
StatePublished - Mar 1992

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine


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