Abstract
Tobacco harm reduction is a public health approach to reduce the impact of cigarette smoking on individuals. Non-combustible alternatives to cigarettes, such as electronic cigarettes (e-cigarettes), deliver nicotine to the user in the absence of combustion. The absence of combustion in e-cigarettes reduces the level of harmful or potentially harmful chemicals in the aerosol generated. This narrative review examines the published literature that studied the chemistry of e-cigarette aerosols, the related toxicology in cell culture and animal models, as well as clinical studies that investigated short- and long-term changes in biomarkers of smoke exposure after switching to e-cigarettes. In the context of the literature reviewed, the evidence supports the harm reduction potential for adult smokers who switch to e-cigarettes.
Original language | English (US) |
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Article number | 67 |
Journal | Substance Abuse: Treatment, Prevention, and Policy |
Volume | 18 |
Issue number | 1 |
DOIs | |
State | Published - Dec 2023 |
Externally published | Yes |
Keywords
- Electronic cigarette
- Harm reduction
- Non-combustible alternatives
- Smoking
- Vaping
ASJC Scopus subject areas
- Health Policy
- Psychiatry and Mental health