TY - JOUR
T1 - Concurrent measurement of skeletal muscle blood flow during exercise with diffuse correlation spectroscopy and Doppler ultrasound
AU - Bangalore-Yogananda, Chandan Ganesh
AU - Rosenberry, Ryan
AU - Soni, Sagar
AU - Liu, Hanli
AU - Nelson, Michael D.
AU - Tian, Fenghua
N1 - Funding Information:
Interdisciplinary Research Project of the University of Texas at Arlington; National Institutes of Health (NIH) (R03EB022956); American Heart Association (AHA) (15BGIA25860045).
Publisher Copyright:
© 2017-2018 Optical Society of America.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Noninvasive, direct measurement of local muscle blood flow in humans remains limited. Diffuse correlation spectroscopy (DCS) is an emerging technique to measure regional blood flow at the microvascular level. In order to better understand the strengths and limitations of this novel technique, we performed a validation study by comparing muscle blood flow changes measured with DCS and Doppler ultrasound during exercise. Nine subjects were measured (all males, 27.4 ± 2.9 years of age) for a rhythmic handgrip exercise at 20% and 50% of individual maximum voluntary contraction (MVC), followed by a postexercise recovery. The results from DCS and Doppler ultrasound were highly correlated (R = 0.99 ± 0.02). DCS was more reliable and less susceptible to motion artifact.
AB - Noninvasive, direct measurement of local muscle blood flow in humans remains limited. Diffuse correlation spectroscopy (DCS) is an emerging technique to measure regional blood flow at the microvascular level. In order to better understand the strengths and limitations of this novel technique, we performed a validation study by comparing muscle blood flow changes measured with DCS and Doppler ultrasound during exercise. Nine subjects were measured (all males, 27.4 ± 2.9 years of age) for a rhythmic handgrip exercise at 20% and 50% of individual maximum voluntary contraction (MVC), followed by a postexercise recovery. The results from DCS and Doppler ultrasound were highly correlated (R = 0.99 ± 0.02). DCS was more reliable and less susceptible to motion artifact.
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U2 - 10.1364/BOE.9.000131
DO - 10.1364/BOE.9.000131
M3 - Article
C2 - 29359092
AN - SCOPUS:85039739018
SN - 2156-7085
VL - 9
SP - 131
EP - 141
JO - Biomedical Optics Express
JF - Biomedical Optics Express
IS - 1
M1 - #306844
ER -